Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA

Stable Identifier
R-RNO-2046091
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA

Tetracosapentaenoyl-CoA (9,12,15,18,21-24:5(n-3)) is further converted by delta 6-desaturase (FADS2) to tetracosahexaenoyl-CoA (6,9,12,15,18,21-24:6(n-3)).

Literature References
PubMed ID Title Journal Year
11988075 The same rat Delta6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis

d'Andréa, S, Guillou, H, Jan, S, Catheline, D, Thibault, JN, Bouriel, M, Rioux, V, Legrand, P

Biochem J 2002
Participants
Catalyst Activity

omega-6 fatty acid desaturase activity of Fads2 [endoplasmic reticulum membrane]

Orthologous Events
Authored
Created
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