Reactome | Fnta [cytosol]

Fnta [cytosol]

Stable Identifier

R-RNO-202872

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

FNTA(59-379), Q04631

Locations in the PathwayBrowser for interactor UniProt:Q02293

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External Reference Information

External Reference

UniProt:Q04631

Gene Names

Fnta

Reference Genes

BioGPS Gene:25318 Fnta

ENSEMBL:ENSRNOG00000014462

KEGG Gene (Rattus norvegicus):25318 Fnta

Monarch:25318 Fnta

NCBI Gene:25318 Fnta

UCSC:Q04631 Fnta

Reference Transcript

RefSeq:NM_012847.1 Fnta

Participates

as an output of

Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha (Rattus norvegicus)

Other forms of this molecule

Fnta [cytosol]

Inferred From

FNTA(59-379) [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_036979.1

PRO

Q04631

RGD

2625

PDB

1N4R, 1N4Q, 1TNB, 1N94, 1FT1, 1N4P, 1TN8, 1TNZ, 1NL4, 3E33, 3E34, 4GTP, 1N9A, 1O1T, 1TNU, 1JCR, 3EU5, 1D8E, 3PZ4, 1D8D, 4GTO, 1FPP, 1FT2, 3KSQ, 1O1R, 4GTM, 1SA5, 1NI1, 2ZIS, 1N4S, 2ZIR, 3KSL, 1O5M, 1N95, 1TNO, 1O1S, 1KZP, 3EUV, 3DPY, 1JCS, 1S64, 8E9E, 1QBQ, 1KZO, 4GTR, 4GTQ, 2R2L, 3E32, 7RNI, 1TNY, 1X81, 1TN7, 3E30, 2BED, 7RN5

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q02293	1	FNTB [cytosol] (R-RNO-2530482)	0.951	16
UniProt:P53610 PGTB1			0.786	7
UniProt:P01116-2 KRAS	8	S-Farn-Me KRAS4B [cytosol] (R-HSA-9654510) pS181-S-Farn-Me KRAS4B [mitochondrial outer membrane] (R-HSA-9653578) pS181-S-Farn-Me KRAS4B [plasma membrane] (R-HSA-9653482) S-Farn-Me KRAS4B [endoplasmic reticulum membrane] (R-HSA-9649690) S-Farn KRAS4B [endoplasmic reticulum membrane] (R-HSA-9649698) S-Farn proKRAS4B [endoplasmic reticulum membrane] (R-HSA-9649693) pro-KRAS4B [cytosol] (R-HSA-9649686) S-Farn-Me KRAS4B [plasma membrane] (R-HSA-9647815)	0.609	3
UniProt:Q63604 Ntrk2	7	p-Y705,Y706-Ntrk2 [plasma membrane] (R-RNO-9037061) p-5Y,S478-Ntrk2 [plasma membrane] (R-RNO-9032964) phospho-p-5Y-NTRK2 [plasma membrane] (R-RNO-9026475) Phosphorylated TrkB receptor [Golgi membrane] (R-RNO-189645) Ntrk2 [Golgi membrane] (R-RNO-189636) p-5Y-Ntrk2 [plasma membrane] (R-RNO-181803) Ntrk2 [plasma membrane] (R-RNO-179527)	0.591	4
UniProt:P62070 RRAS2	1	RRAS2 [plasma membrane] (R-HSA-9715189)	0.589	5

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