Reactome | Sirpa [plasma membrane]

Sirpa [plasma membrane]

Stable Identifier

R-RNO-197571-6

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

SIRPG, P97710

Locations in the PathwayBrowser

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Hemostasis (Rattus norvegicus)

- Cell surface interactions at the vascular wall (Rattus norvegicus)
  - CD47 binds SIRP (Rattus norvegicus)
    - CD47-binding SIRPs [plasma membrane] (Rattus norvegicus)
      - Homologues of SIRPG [plasma membrane] (Rattus norvegicus)
        
        Sirpa [plasma membrane] (Rattus norvegicus)
    - CD47-binding SIRPs:CD47 [plasma membrane] (Rattus norvegicus)
      - CD47-binding SIRPs [plasma membrane] (Rattus norvegicus)
        
        Homologues of SIRPG [plasma membrane] (Rattus norvegicus)
        
        Sirpa [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P97710 Sirpa

Gene Names

Sirpa, Bit, Mfr, Ptpns1, Shps1, Sirp

Chain

signal peptide:1-31, chain:32-509

Reference Genes

BioGPS Gene:25528 Sirpa

ENSEMBL:ENSRNOG00000004763 Sirpa

KEGG Gene (Rattus norvegicus):25528 Sirpa

Monarch:25528 Sirpa

NCBI Gene:25528 Sirpa

UCSC:P97710 Sirpa

Reference Transcript

Other Identifiers

10839790

1367881_at

1370574_a_at

17766160

25528

5625701

5654581

5947813

6084995

6379495

6497518

6556276

6557257

6610360

6670946

6726723

AF055065_s_at

A_43_P14890

A_64_P000678

A_64_P000683

D38468_s_at

D85183_s_at

GE1275583

ILMN_1360759

PH_rn_0012083

Participates

as a member of

Homologues of SIRPG [plasma membrane] (Rattus norvegicus)

Other forms of this molecule

pSirpa_Rat [plasma membrane]

Sirpa_Rat [plasma membrane]

phospho-Sirpa [plasma membrane]

Sirpa [tertiary granule membrane]

Sirpa [plasma membrane]

Sirpa [secretory granule membrane]

Sirpa [ficolin-1-rich granule membrane]

Sirpa [plasma membrane]

Inferred From

SIRPG [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_037148.2, XP_017446986.1

Ensembl

ENSRNOT00000006408, ENSRNOP00000006408, ENSRNOG00000004763

PRO

P97710

RGD

3449

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q06124 PTPN11	4	PTPN11 [nucleoplasm] (R-HSA-8937745) p-Y546-PTPN11 [cytosol] (R-HSA-1369081) p-Y546,Y584-PTPN11 [cytosol] (R-HSA-162573) PTPN11 [cytosol] (R-HSA-162563)	0.564	3
UniProt:P41499 Ptpn11	4	Ptpn11 [nucleoplasm] (R-RNO-8937745) p-Y-Shp2 [cytosol] (R-RNO-1369098) phospho-Ptpn11 [cytosol] (R-RNO-162573) Ptpn11 [cytosol] (R-RNO-548923)	0.544	3
UniProt:Q9R044 Nphs1	4	p-Nephrin_RAT [plasma membrane] (R-RNO-451715) Nephrin_RAT [plasma membrane] (R-RNO-451392) phospho-Nphs1 [plasma membrane] (R-RNO-373636) Nphs1 [plasma membrane] (R-RNO-8981500)	0.524	2