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CSNK1A1 [cytosol]
Stable Identifier
R-RNO-195263
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
P97633
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Hedgehog (Rattus norvegicus)
Hedgehog 'off' state (Rattus norvegicus)
GLI3 is processed to GLI3R by the proteasome (Rattus norvegicus)
CK1 phosphorylates p-GLI3 (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Signaling by WNT (Rattus norvegicus)
Degradation of beta-catenin by the destruction complex (Rattus norvegicus)
AXIN is phosphorylated in the destruction complex (Rattus norvegicus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Assembly of the destruction complex (Rattus norvegicus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Rattus norvegicus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Rattus norvegicus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Association of beta-catenin with the destruction complex (Rattus norvegicus)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Beta-catenin phosphorylation cascade (Rattus norvegicus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Rattus norvegicus)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Rattus norvegicus)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Rattus norvegicus)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Rattus norvegicus)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Degradation of ubiquitinated beta catenin by the proteasome (Rattus norvegicus)
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Rattus norvegicus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Rattus norvegicus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Rattus norvegicus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Rattus norvegicus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Rattus norvegicus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Rattus norvegicus)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Rattus norvegicus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
Phosphorylation of APC component of the destruction complex (Rattus norvegicus)
CK1alpha (GSK3) [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
TCF dependent signaling in response to WNT (Rattus norvegicus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Rattus norvegicus)
Beta-catenin is released from the destruction complex (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
CSNK1A1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P97633 Csnk1a1
Gene Names
Csnk1a1
Chain
initiator methionine:, chain:2-325
Reference Genes
BioGPS Gene:113927 Csnk1a1
KEGG Gene (Rattus norvegicus):113927 Csnk1a1
Monarch:113927 Csnk1a1
NCBI Gene:113927 Csnk1a1
UCSC:P97633 Csnk1a1
Reference Transcript
RefSeq:NM_053615.1 Csnk1a1
Participates
as a component of
p-AXIN:CK1alpha:GSK3B:phospho-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Rattus norvegicus)
as an input of
Assembly of the destruction complex (Rattus norvegicus)
as a member of
CK1alpha (GSK3) [cytosol] (Rattus norvegicus)
as an output of
Beta-catenin is released from the destruction complex (Rattus norvegicus)
Other forms of this molecule
CSNK1A1 [cilium]
Csnk1a1 [cytosol]
Inferred From
CSNK1A1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_446067.1
IntEnz
2.7.11.1
PRO
P97633
RGD
71098
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