Prdm4 (Sc1) binds to p75NTR

Stable Identifier
R-RNO-194493
Type
Reaction
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
Prdm4 (Sc1) binds to p75NTR

PRDM4, usually named SC1, for Schwann Cell factor 1, is a zinc finger protein that functions as a repressor of transcription. It is present in many tissues, and abundant in brain. It interacts with the NGF:p75NTR complex to signal cell cycle arrest. It is unclear whether it already forms a complex with p75NTR before NGF binding to p75.

Literature References
PubMed ID Title Journal Year
10485890 Identification of a zinc finger protein whose subcellular distribution is regulated by serum and nerve growth factor

Chittka, A, Chao, MV

Proc Natl Acad Sci U S A 1999
Participants
Orthologous Events
Authored
Reviewed
Created