Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Kl [plasma membrane]
Stable Identifier
R-RNO-190198
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
KL-1, Q9Z2Y9
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
PIP3 activates AKT signaling (Rattus norvegicus)
Negative regulation of the PI3K/AKT network (Rattus norvegicus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activator:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF/MAP kinase cascade (Rattus norvegicus)
RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)
RAS GEFs [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by FGFR (Rattus norvegicus)
Signaling by FGFR1 (Rattus norvegicus)
Downstream signaling of activated FGFR1 (Rattus norvegicus)
Activated FGFR1 binds FLRT1,2,3 (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:FLRT [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
FRS-mediated FGFR1 signaling (Rattus norvegicus)
Activated FGFR1 binds FRS2 (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1 binds FRS3 (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1 phosphorylates FRS2 (Rattus norvegicus)
Activated FGFR1:FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1 phosphorylates FRS3 (Rattus norvegicus)
Activated FGFR1:FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS bind to PPTN11 (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS binds GRB2:SOS1 (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR1:p-FRS:PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR1:p-FRS:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS3 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
PI-3K cascade:FGFR1 (Rattus norvegicus)
Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Phospholipase C-mediated cascade: FGFR1 (Rattus norvegicus)
Activated FGFR1 binds PLCG1 (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
activated FGFR1:PLCG1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1 phosphorylates PLCG1 (Rattus norvegicus)
activated FGFR1:PLCG1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
activated FGFR1:p-4Y-PLCG1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
p-4Y-PLCG1 dissociates from activated FGFR1 (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
activated FGFR1:p-4Y-PLCG1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
SHC-mediated cascade:FGFR1 (Rattus norvegicus)
Activated FGFR1 binds SHC1 (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:SHC1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1 phosphorylates SHC1 (Rattus norvegicus)
Activated FGFR1:SHC1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Rattus norvegicus)
Activated FGFR1:p-SHC1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)
Activated FGFR1:p-SHC1:GRB2:SOS1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-SHC1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
FGFR1 ligand binding and activation (Rattus norvegicus)
FGFR1c and Klotho ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
FGF23 bound to Klotho and FGFR1c [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
FGFR1c binds to Klotho-bound FGF23 (Rattus norvegicus)
FGF23 bound to Klotho and FGFR1c [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Negative regulation of FGFR1 signaling (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Rattus norvegicus)
Activated FGFR1:FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-8T-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
CBL ubiquitinates FRS2 and FGFR1 (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Ub-Activated FGFR1 complex:Ub-p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR1:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR1 [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Signaling by Insulin receptor (Rattus norvegicus)
Insulin receptor signalling cascade (Rattus norvegicus)
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
PI3K-containing complexes [cytosol] (Rattus norvegicus)
Activated FGFR bound to PI3K [cytosol] (Rattus norvegicus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Rattus norvegicus)
IGF1R signaling cascade (Rattus norvegicus)
IRS-related events triggered by IGF1R (Rattus norvegicus)
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
PI3K-containing complexes [cytosol] (Rattus norvegicus)
Activated FGFR bound to PI3K [cytosol] (Rattus norvegicus)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2:p-PTPN11 [plasma membrane] (Rattus norvegicus)
Activated FGFR:p-FRS2 [plasma membrane] (Rattus norvegicus)
Activated FGFR [plasma membrane] (Rattus norvegicus)
Activated FGFR1c bound to FGF23:Klotho [plasma membrane] (Rattus norvegicus)
Klotho bound to FGF23 [plasma membrane] (Rattus norvegicus)
Klotho homodimer [plasma membrane] (Rattus norvegicus)
Klotho [extracellular region] (Rattus norvegicus)
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Kl [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q9Z2Y9
Gene Names
Kl
Reference Genes
BioGPS Gene:83504 Kl
ENSEMBL:ENSRNOG00000001092
ENSEMBL:ENSRNOG00000001092.6 Kl
KEGG Gene (Rattus norvegicus):83504 Kl
Monarch:83504 Kl
NCBI Gene:83504 Kl
UCSC:Q9Z2Y9 Kl
Reference Transcript
RefSeq:NM_031336.1 Kl
Other Identifiers
10759762
1369361_at
17675342
5732392
5813008
6098520
6196624
6247831
6356246
6442366
6471155
6503501
6680141
6689224
83504
AB017820_at
A_43_P12558
A_64_P041134
GE13062
GO:0003824
GO:0004553
GO:0005104
GO:0005975
GO:0006091
GO:0006112
GO:0008340
GO:0016020
GO:0016787
GO:0017134
GO:0023052
GO:0030501
GO:0048856
GO:0055065
GO:0055074
GO:0090080
ILMN_1353042
PH_rn_0010681
Participates
as a component of
Membrane-bound Klotho homodimer [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
Kl [extracellular region]
Inferred From
KL-1 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_112626.1
Ensembl
ENSRNOG00000001092
,
ENSRNOP00000001449
,
ENSRNOT00000001449
PRO
Q9Z2Y9
RGD
620396
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text