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Epn1 [plasma membrane]
Stable Identifier
R-RNO-182952
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
EPN1, O88339
Locations in the PathwayBrowser for interactor UniProt:P18484 Ap2a2
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by EGFR (Rattus norvegicus)
EGFR downregulation (Rattus norvegicus)
EGFR binds EPS15, EPN1, EPS15L1 (Rattus norvegicus)
Epn1 [plasma membrane] (Rattus norvegicus)
EGFR non-clathrin mediated endocytosis (Rattus norvegicus)
Epn1 [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:O88339
Gene Names
Epn1
Reference Genes
BioGPS Gene:117277 Epn1
ENSEMBL:ENSRNOG00000015753
KEGG:rno:117277 Epn1
Monarch:117277 Epn1
NCBI Gene:117277 Epn1
UCSC:O88339 Epn1
Reference Transcript
RefSeq:NM_057136.2 Epn1
Participates
as a component of
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:Ub-CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:CIN85:Endophilin:Epsin:Eps15L1:Eps15 [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:p-EPS15:HGS:STAM [plasma membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:EPN1:EPS15L1:EPS15:HGS:STAM [plasma membrane] (Rattus norvegicus)
as an input of
EGFR non-clathrin mediated endocytosis (Rattus norvegicus)
EGFR binds EPS15, EPN1, EPS15L1 (Rattus norvegicus)
Other forms of this molecule
Epn1 [cytosol]
Inferred From
EPN1 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_476477.1
PRO
O88339
RGD
619772
PDB
1EYH
,
1EDU
,
1KY6
,
1H0A
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P18484 Ap2a2
8
Ap2a2 [endolysosome membrane]
(R-RNO-6784819)
Ap2a2 [ficolin-1-rich granule membrane]
(R-RNO-6800414)
Ap2a2 [secretory granule membrane]
(R-RNO-6800412)
Ap2a2 [endocytic vesicle membrane]
(R-RNO-416635)
Ap2a2 [clathrin-coated endocytic vesicle membrane]
(R-RNO-5138448)
Ap2a2 [cytosol]
(R-RNO-182155)
Adaptor Protein 2 alpha 2 subunit [plasma membrane]
(R-RNO-182073)
Ap2a2 [plasma membrane]
(R-RNO-177502)
0.775
6
UniProt:P17427
7
Ap2a2 [endolysosome membrane]
(R-MMU-6784819)
Ap2a2 [ficolin-1-rich granule membrane]
(R-MMU-6800414)
Ap2a2 [secretory granule membrane]
(R-MMU-6800412)
Ap2a2 [endocytic vesicle membrane]
(R-MMU-416635)
Ap2a2 [clathrin-coated endocytic vesicle membrane]
(R-MMU-5138448)
Ap2a2 [cytosol]
(R-MMU-182155)
Ap2a2 [plasma membrane]
(R-MMU-177502)
0.743
4
UniProt:Q06407
2
RGA2 [cytosol]
(R-SCE-8873920-6)
RGA2 [cytosol]
(R-SCE-2976016-6)
0.527
2
UniProt:P39083
2
RGA1 [cytosol]
(R-SCE-8873920-4)
RGA1 [cytosol]
(R-SCE-2976016-4)
0.527
2
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