Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Spry2 [cytosol]
Stable Identifier
R-RNO-182949
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
SPRY2, Q5HZA2
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by EGFR (Rattus norvegicus)
EGFR downregulation (Rattus norvegicus)
CBL binds and ubiquitinates phosphorylated Sprouty (Rattus norvegicus)
SPRY1/2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
Sprouty lures CBL away from EGFR (Rattus norvegicus)
CBL:SPRY1/2 [cytosol] (Rattus norvegicus)
SPRY1/2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
Signaling by FGFR (Rattus norvegicus)
Signaling by FGFR1 (Rattus norvegicus)
Negative regulation of FGFR1 signaling (Rattus norvegicus)
Spry regulation of FGF signaling (Rattus norvegicus)
PPA2A dephosphorylates SPRY2 (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
SPRY2 is serine phosphorylated in response to MAPK activation (Rattus norvegicus)
SPRY2:B-RAF [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
SPRY2 translocates to the plasma membrane (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
Signaling by FGFR2 (Rattus norvegicus)
Negative regulation of FGFR2 signaling (Rattus norvegicus)
Spry regulation of FGF signaling (Rattus norvegicus)
PPA2A dephosphorylates SPRY2 (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
SPRY2 is serine phosphorylated in response to MAPK activation (Rattus norvegicus)
SPRY2:B-RAF [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
SPRY2 translocates to the plasma membrane (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
Signaling by FGFR3 (Rattus norvegicus)
Negative regulation of FGFR3 signaling (Rattus norvegicus)
Spry regulation of FGF signaling (Rattus norvegicus)
PPA2A dephosphorylates SPRY2 (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
SPRY2 is serine phosphorylated in response to MAPK activation (Rattus norvegicus)
SPRY2:B-RAF [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
SPRY2 translocates to the plasma membrane (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
Signaling by FGFR4 (Rattus norvegicus)
Negative regulation of FGFR4 signaling (Rattus norvegicus)
Spry regulation of FGF signaling (Rattus norvegicus)
PPA2A dephosphorylates SPRY2 (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
SPRY2 is serine phosphorylated in response to MAPK activation (Rattus norvegicus)
SPRY2:B-RAF [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
SPRY2 translocates to the plasma membrane (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
Spry2 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q5HZA2
Gene Names
Spry2
Reference Genes
BioGPS Gene:306141 Spry2
ENSEMBL:ENSRNOG00000010058
ENSEMBL:ENSRNOG00000010058.7 Spry2
KEGG Gene (Rattus norvegicus):306141 Spry2
Monarch:306141 Spry2
NCBI Gene:306141 Spry2
UCSC:Q5HZA2 Spry2
Reference Transcript
RefSeq:NM_001012046.1 Spry2
RefSeq:XM_006252438.3 Spry2
Other Identifiers
10785773
1374864_at
1377101_at
17705145
306141
5629727
5678378
5734034
5861141
5866872
5879211
6177828
6293279
6424165
A_44_P253012
A_44_P794476
GE1107694
GE1143320
GE1268013
GE13802
GO:0000132
GO:0000278
GO:0005634
GO:0005829
GO:0005856
GO:0007010
GO:0007163
GO:0007275
GO:0007605
GO:0008285
GO:0008543
GO:0009966
GO:0010719
GO:0012501
GO:0016020
GO:0023052
GO:0030154
GO:0030324
GO:0030512
GO:0031345
GO:0036211
GO:0040037
GO:0042472
GO:0043066
GO:0043226
GO:0045165
GO:0045742
GO:0046580
GO:0048754
GO:0048856
GO:0050877
GO:0051387
GO:0055105
GO:0060425
GO:0060437
GO:0060449
GO:0060541
GO:0070371
GO:0070373
GO:0098772
GO:0140678
GO:1902747
GO:1990830
ILMN_1376572
PH_rn_0008021
rc_AA850753_at
rc_AI045635_at
rc_AI059142_at
Participates
as a component of
SPRY2:B-RAF [cytosol] (Rattus norvegicus)
PPA2A(A:C):SPRY2 [cytosol] (Rattus norvegicus)
as a member of
SPRY1/2 [cytosol] (Rattus norvegicus)
Other forms of this molecule
phospho-Spry2 [cytosol]
phospho-Spry2 [plasma membrane]
phospho-Spry2 [plasma membrane]
phospho-Spry2 [cytosol]
Spry2 [plasma membrane]
phospho-Spry2 [cytosol]
Inferred From
SPRY2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001012046.1
,
XP_006252500.1
Ensembl
ENSRNOT00000106586
,
ENSRNOP00000077712
,
ENSRNOT00000097462
,
ENSRNOG00000010058
,
ENSRNOT00000013342
,
ENSRNOP00000013342
,
ENSRNOP00000081271
RGD
1311472
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text