Reactome | MASP1(20-448) [extracellular region]

MASP1(20-448) [extracellular region]

Stable Identifier

R-RNO-182685

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

extracellular region

Synonyms

Q8CHN8

Locations in the PathwayBrowser

Expand all

Immune System (Rattus norvegicus)

- Innate Immune System (Rattus norvegicus)
  - Complement cascade (Rattus norvegicus)
    - Initial triggering of complement (Rattus norvegicus)
      - Conversion of C2 into C2a and C2b (Rattus norvegicus)
        
        C4 activators [plasma membrane] (Rattus norvegicus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Rattus norvegicus)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)
        
        MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)
      - Conversion of C4 into C4a and C4b (Rattus norvegicus)
        
        C4 activators [plasma membrane] (Rattus norvegicus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Rattus norvegicus)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)
        
        MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)
      - Creation of C4 and C2 activators (Rattus norvegicus)
        
        Lectin pathway of complement activation (Rattus norvegicus)
        
        Activation of MASPs (Rattus norvegicus)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Rattus norvegicus)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)
        
        Ficolin-2:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)
        
        MBL:activated MASPs:mannose-based carbohydrates [plasma membrane] (Rattus norvegicus)
        
        MBL2 dodecamer:2xActivated MASP1:2xActivated MASP2-1 [extracellular region] (Rattus norvegicus)
        
        Activated MASP1 [extracellular region] (Rattus norvegicus)
        
        MASP1(20-448) [extracellular region] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:Q8CHN8

Reference Genes

BioGPS Gene:64023

ENSEMBL:ENSRNOG00000001827

ENSEMBL:ENSRNOG00000001827.9

ENSEMBL:ENSRNOG00055004619

ENSEMBL:ENSRNOG00060013056

ENSEMBL:ENSRNOG00065003514

KEGG Gene (Rattus norvegicus):64023

Monarch:64023

NCBI Gene:64023

UCSC:Q8CHN8

Reference Transcript

Other Identifiers

10751948

1371116_at

1389543_at

17666587

5737282

5745131

5754265

5917987

6005244

6034884

6047844

6067377

6159190

6262013

6304874

6358306

64023

6417919

6546165

6597860

6626156

6658309

6663795

6699677

AF004661_at

A_44_P189476

A_44_P472974

A_64_P163358

GE15721

GO:0003824

GO:0004252

GO:0005509

GO:0006508

GO:0016787

GO:0140096

rc_AA801013_at

Participates

as a component of

Activated MASP1 [extracellular region] (Rattus norvegicus)

Other forms of this molecule

MASP1(20-699) [extracellular region]

MASP1(449-699) [extracellular region]

Inferred From

MASP1(20-448) [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_006248588.1, NP_071593.1, XP_008767026.1

Ensembl

ENSRNOP00000044812, ENSRNOP00000079792, ENSRNOT00000047678, ENSRNOT00000094154, ENSRNOG00000001827

PRO

Q8CHN8

RGD

620213

PDB

3POE, 3POJ, 3POB, 3POI, 3POF, 5CKQ, 3POG