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What is Reactome ?
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Adaptor protein complex 2 (AP-2) large adaptins [cytosol]
Stable Identifier
R-RNO-182144
Type
Set [DefinedSet]
Species
Rattus norvegicus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by WNT (Rattus norvegicus)
Beta-catenin independent WNT signaling (Rattus norvegicus)
PCP/CE pathway (Rattus norvegicus)
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Rattus norvegicus)
FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Rattus norvegicus)
clathrin:AP-2 [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
WNT5A-dependent internalization of FZD4 (Rattus norvegicus)
WNT5A:FZD4 is endocytosed (Rattus norvegicus)
WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] (Rattus norvegicus)
clathrin:AP-2 [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Rattus norvegicus)
WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] (Rattus norvegicus)
clathrin:AP-2 [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
clathrin:AP-2 [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
Clathrin-mediated endocytosis (Rattus norvegicus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
BAR domain proteins recruit dynamin (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Cargo recognition for clathrin-mediated endocytosis (Rattus norvegicus)
AP-2 directly binds some endocytic cargo (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
AP2:chlorpromazine [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
AP2 binds chlorpromazine (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
AP2:chlorpromazine [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
ARBB recruits GPCRs into clathrin-coated pits (Rattus norvegicus)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Clathrin recruits PIK3C2A (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Clathrin recruits auxilins to the clathrin-coated vesicle (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Endophilins recruit synaptojanins to the clathrin-coated pit (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
F- and N- BAR domain proteins bind the clathrin-coated pit (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Initial binding of AP-2 and clathrin to PI(4,5)P2 (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
RAB5 and GAPVD1 bind AP-2 (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)
Clathrin-coated vesicle [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Recruitment of AP-2 complex and clathrin (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Rattus norvegicus)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Rattus norvegicus)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
CLASP proteins:cargo [plasma membrane] (Rattus norvegicus)
AP-2:cargo [plasma membrane] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
Adaptor protein complex 2 (AP-2) large adaptins [cytosol] (Rattus norvegicus)
Participants
members
AP2A2(1-939) [cytosol]
(Rattus norvegicus)
AP2A1 [cytosol]
(Rattus norvegicus)
Participates
as a component of
p-T156 AP-2 Complex [cytosol] (Rattus norvegicus)
AP-2 Complex [cytosol] (Rattus norvegicus)
Inferred From
Adaptor protein complex 2 (AP-2) large adaptins [cytosol]
(Homo sapiens)
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