Formation of clathrin-coated vesicle

Stable Identifier
R-RNO-177478
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Formation of clathrin-coated vesicle
Both BDNF and NGF treatment recruits clathrin and AP2 (adaptor protein 2) proteins to the plasma membrane. Clathrin is the major protein of the polyhedral coat of vesicles. The AP2 complex mediates both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Literature References
PubMed ID Title Journal Year
11007890 NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking

Mobley, WC, Brodsky, FM, Howe, CL, Wilde, A, Beattie, EC

J Neurosci 2000
Participants
Input
Output
Orthologous Events
Formation of clathrin-coated vesicle (Homo sapiens)
Reviewed
Greene, LA  (2007-11-08)
Created
Jassal, B  (2006-03-31)
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