Reactome | PSMC5 [nucleoplasm]

PSMC5 [nucleoplasm]

Stable Identifier

R-RNO-174312

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

P62198

Locations in the PathwayBrowser

Expand all

Cellular responses to stimuli (Rattus norvegicus)

- Cellular responses to stress (Rattus norvegicus)
  - Cellular response to chemical stress (Rattus norvegicus)
    - KEAP1-NFE2L2 pathway (Rattus norvegicus)
      - Nuclear events mediated by NFE2L2 (Rattus norvegicus)
        
        GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 (Rattus norvegicus)
        
        Ub,pS335,S338,T NFE2L2 is degraded (Rattus norvegicus)
        
        26S proteasome [nucleoplasm] (Rattus norvegicus)
        
        PSMC5 [nucleoplasm] (Rattus norvegicus)

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Deubiquitination (Rattus norvegicus)
    - Ub-specific processing proteases (Rattus norvegicus)
      - USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Rattus norvegicus)
        
        USP37:RUVLB1:PSMC5:CCNA1,CCNA2 [nucleoplasm] (Rattus norvegicus)
        
        USP37:RUVLB1:PSMC5 [nucleoplasm] (Rattus norvegicus)
        
        PSMC5 [nucleoplasm] (Rattus norvegicus)
        
        USP37:RUVLB1:PSMC5:PolyUb-CCNA1,PolyUb-CCNA2 [nucleoplasm] (Rattus norvegicus)
        
        USP37:RUVLB1:PSMC5 [nucleoplasm] (Rattus norvegicus)
        
        PSMC5 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P62198

Reference Genes

BioGPS Gene:81827

ENSEMBL:ENSRNOG00000010038

ENSEMBL:ENSRNOG00000010038.7

KEGG Gene (Rattus norvegicus):81827

Monarch:81827

NCBI Gene:81827

UCSC:P62198

Reference Transcript

RefSeq:NM_031149.1

Other Identifiers

10739135

1367833_at

1381276_at

17652110

5633701

5676718

5744768

5814129

6069784

6179860

6216297

6231422

6252768

6366353

6471850

6569211

6587295

81827

AB000491_at

A_43_P12543

GE21229

GO:0003824

GO:0005524

GO:0016787

GO:0016887

GO:0140657

ILMN_1354016

PH_rn_0021626

Participates

as a component of

Other forms of this molecule

PSMC5 [cytosol]

Inferred From

PSMC5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_112411.1

Ensembl

ENSRNOG00000010038, ENSRNOT00000118001, ENSRNOP00000079284

PRO

P62198

RGD

708376

PDB

6EPE, 6EPC, 6EPF, 6EPD