Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Ube2d1 [nucleoplasm]
Stable Identifier
R-RNO-174197
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
UBE2D1, D3ZDK2
Locations in the PathwayBrowser
Expand all
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
Regulation of mitotic cell cycle (Rattus norvegicus)
APC/C-mediated degradation of cell cycle proteins (Rattus norvegicus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Rattus norvegicus)
APC/C:Cdh1 polyubiquitinates SKP2 (Rattus norvegicus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
APC/C:Cdh1-mediated degradation of Skp2 (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
RB1 recruits APC/C:Cdh1 complex to SKP2 (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Rattus norvegicus)
Phosphorylation of the APC/C (Rattus norvegicus)
Free APC/C phosphorylated by Cyclin B:Cdc2 (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Free APC/C phosphorylated by Plk1 (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Autodegradation of Cdh1 by Cdh1:APC/C (Rattus norvegicus)
Degradation of multiubiquitinated Cdh1 (Rattus norvegicus)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Rattus norvegicus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Multiubiquitination of APC/C-associated Cdh1 (Rattus norvegicus)
multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Rattus norvegicus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Regulation of APC/C activators between G1/S and early anaphase (Rattus norvegicus)
Association of Cyclin A:Cdk2 with Cdh1 (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Dissociation of phospho-Cdh1 from the APC/C complex (Rattus norvegicus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Rattus norvegicus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular Senescence (Rattus norvegicus)
Senescence-Associated Secretory Phenotype (SASP) (Rattus norvegicus)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Rattus norvegicus)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Cdh1:APC/C complex binds EHMT1:EHMT2 (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Rattus norvegicus)
EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Rattus norvegicus)
Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Cellular response to hypoxia (Rattus norvegicus)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Rattus norvegicus)
Nuclear VBC complex ubiquitinylates HIF-alpha (Rattus norvegicus)
UBE2D1,2,3 [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
UBE2D1,2,3:Ubiquitin [nucleoplasm] (Rattus norvegicus)
UBE2D1,2,3 [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
DNA Replication (Rattus norvegicus)
DNA Replication Pre-Initiation (Rattus norvegicus)
Assembly of the pre-replicative complex (Rattus norvegicus)
The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Rattus norvegicus)
phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Rattus norvegicus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Rattus norvegicus)
Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Rattus norvegicus)
Nuclear ubiquitin ligase [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Deubiquitination (Rattus norvegicus)
Ovarian tumor domain proteases (Rattus norvegicus)
OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Rattus norvegicus)
OTUB1,(OTUB2):UBE2D1,ESR1 [nucleoplasm] (Rattus norvegicus)
UBE2D1,ESR1 [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
UBE2D1,ESR1 [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Signaling by TGFB family members (Rattus norvegicus)
Signaling by BMP (Rattus norvegicus)
Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Rattus norvegicus)
Nuclear ubiquitin ligase [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Rattus norvegicus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Rattus norvegicus)
Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Rattus norvegicus)
Nuclear ubiquitin ligase [nucleoplasm] (Rattus norvegicus)
Ube2d1 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:D3ZDK2
Gene Names
Ube2d1
Reference Genes
BioGPS Gene:361831 Ube2d1
ENSEMBL:ENSRNOG00000000611
ENSEMBL:ENSRNOG00000000611.8 Ube2d1
KEGG Gene (Rattus norvegicus):361831 Ube2d1
Monarch:361831 Ube2d1
NCBI Gene:361831 Ube2d1
UCSC:D3ZDK2 Ube2d1
Reference Transcript
RefSeq:NM_001108530.1 Ube2d1
Other Identifiers
10829694
1385548_at
1390259_at
17754631
361831
5618531
5651825
5969252
6015659
6082545
6175618
6183548
6349704
6503485
6680077
AA942808_at
A_44_P274550
A_64_P000480
GE1200258
GE12780
ILMN_1351247
PH_rn_0010547
rc_AI231279_at
Participates
as a member of
UBE2D1,ESR1 [nucleoplasm] (Rattus norvegicus)
UBE2D1,2,3 [nucleoplasm] (Rattus norvegicus)
Nuclear ubiquitin ligase [nucleoplasm] (Rattus norvegicus)
as a component of
phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
Ube2d1 [cytosol]
Ube2d1 [cytosol]
Inferred From
UBE2D1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001102000.1
IntEnz
2.3.2.24
Ensembl
ENSRNOT00000000750
,
ENSRNOP00000000750
,
ENSRNOG00000000611
PRO
D3ZDK2
RGD
1307886
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
