Reactome | Ccr5 [plasma membrane]

Ccr5 [plasma membrane]

Stable Identifier

R-RNO-171279

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

CCR5, O08556

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CCL4,(CCL4L):CCR5,CCR1 [plasma membrane] (Rattus norvegicus)
        
        CCR5, CCR1 [plasma membrane] (Rattus norvegicus)
        
        Ccr5 [plasma membrane] (Rattus norvegicus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Rattus norvegicus)
        
        CCR3,4,5 [plasma membrane] (Rattus norvegicus)
        
        Ccr5 [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CCL4,(CCL4L):CCR5,CCR1 [plasma membrane] (Rattus norvegicus)
        
        CCR5, CCR1 [plasma membrane] (Rattus norvegicus)
        
        Ccr5 [plasma membrane] (Rattus norvegicus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Rattus norvegicus)
        
        CCR3,4,5 [plasma membrane] (Rattus norvegicus)
        
        Ccr5 [plasma membrane] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Chemokine receptors bind chemokines (Rattus norvegicus)
        
        Receptors CCR3, 4 and 5 bind CCL5 ligand (Rattus norvegicus)
        
        CCR3,4,5 [plasma membrane] (Rattus norvegicus)
        
        Ccr5 [plasma membrane] (Rattus norvegicus)
        
        CCR3,4,5:CCL5(24-91) [plasma membrane] (Rattus norvegicus)
        
        CCR3,4,5 [plasma membrane] (Rattus norvegicus)
        
        Ccr5 [plasma membrane] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:O08556

Gene Names

Ccr5

Reference Genes

BioGPS Gene:117029 Ccr5

ENSEMBL:ENSRNOG00000049115

ENSEMBL:ENSRNOG00055002419

ENSEMBL:ENSRNOG00060023387

ENSEMBL:ENSRNOG00065000760

KEGG Gene (Rattus norvegicus):117029 Ccr5

Monarch:117029 Ccr5

NCBI Gene:117029 Ccr5

UCSC:O08556 Ccr5

Reference Transcript

RefSeq:NM_053960.3 Ccr5

Participates

as a member of

Inferred From

CCR5 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_446412.2

ZINC target

O08556

PRO

O08556

ZINC - Predictions - Purchasable

CCR5_RAT

RGD

620596

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