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Mapk8 [cytosol]
Stable Identifier
R-RNO-168141
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
MAPK8, P49185
Locations in the PathwayBrowser for interactor UniProt:P50232 SYT4
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-1 family signaling (Rattus norvegicus)
Interleukin-38 signaling (Rattus norvegicus)
MAPK8 phosphorylation (Rattus norvegicus)
Mapk8 [cytosol] (Rattus norvegicus)
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Intrinsic Pathway for Apoptosis (Rattus norvegicus)
Activation of BH3-only proteins (Rattus norvegicus)
Activation of BIM and translocation to mitochondria (Rattus norvegicus)
Phosphorylation of BIM by JNK (Rattus norvegicus)
Mapk8 [cytosol] (Rattus norvegicus)
Activation of BMF and translocation to mitochondria (Rattus norvegicus)
Phosphorylation of DLC2 by MAPK8 (Rattus norvegicus)
Mapk8 [cytosol] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
p75 NTR receptor-mediated signalling (Rattus norvegicus)
Cell death signalling via NRAGE, NRIF and NADE (Rattus norvegicus)
NRAGE signals death through JNK (Rattus norvegicus)
GTP-bound RAC contributes to JNK activation (Rattus norvegicus)
Mapk8 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P49185 Mapk8
Gene Names
Mapk8, Jnk1, Prkm8
Chain
chain:1-411
Reference Genes
BioGPS Gene:116554 Mapk8
KEGG:rno:116554 Mapk8
Monarch:116554 Mapk8
NCBI Gene:116554 Mapk8
UCSC:P49185 Mapk8
Reference Transcript
RefSeq:NM_053829.2 Mapk8
Participates
as an input of
GTP-bound RAC contributes to JNK activation (Rattus norvegicus)
MAPK8 phosphorylation (Rattus norvegicus)
as a member of
MAPK8,9,10 [cytosol] (Rattus norvegicus)
Other forms of this molecule
JNK1 [nucleoplasm]
JNK1 [cytosol]
Phospho-Jnk1 [cytosol]
Jnk1 [cytosol]
phospho-Mapk8 [cytosol]
phospho-Mapk8 [nucleoplasm]
Inferred From
MAPK8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_446281.2
ZINC - Substances
MK08_RAT
ZINC target
P49185
PRO
P49185
GlyGen
P49185
RGD
621506
ZINC - Predictions - Purchasable
MK08_RAT
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P19493
2
Gria4 [endocytic vesicle membrane]
(R-RNO-416303)
Gria4 [plasma membrane]
(R-RNO-392229)
0.544
2
UniProt:P19491-3 GRIA2
0.544
2
UniProt:P50232 SYT4
0.508
5
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