Reactome | Ntf4 [extracellular region]

Ntf4 [extracellular region]

Stable Identifier

R-RNO-167063

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

extracellular region

Synonyms

NTF4, P34131

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
  - Signaling by NTRKs (Rattus norvegicus)
    - Signaling by NTRK2 (TRKB) (Rattus norvegicus)
      - Activated NTRK2 signals through FRS2 and FRS3 (Rattus norvegicus)
        
        Activated NTRK2 binds FRS2 (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 homodimer [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4 homodimer [extracellular region] (Rattus norvegicus)
        
        Ntf4 [extracellular region] (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2:FRS2 [plasma membrane] (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 homodimer [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4 homodimer [extracellular region] (Rattus norvegicus)
        
        Ntf4 [extracellular region] (Rattus norvegicus)
        
        NTRK2-phosphorylated FRS2 binds GRB2 (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2:p-Y-FRS2 [plasma membrane] (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 homodimer [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4 homodimer [extracellular region] (Rattus norvegicus)
        
        Ntf4 [extracellular region] (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2:p-Y-FRS2:GRB2-1:SOS1 [plasma membrane] (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2:p-Y-FRS2 [plasma membrane] (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 homodimer [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4 homodimer [extracellular region] (Rattus norvegicus)
        
        Ntf4 [extracellular region] (Rattus norvegicus)
      - Activated NTRK2 signals through PLCG1 (Rattus norvegicus)
        
        Activated PCLG1 dissociates from NTRK2 (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 homodimer [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4 homodimer [extracellular region] (Rattus norvegicus)
        
        Ntf4 [extracellular region] (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2:p-4Y-PLCG1 [plasma membrane] (Rattus norvegicus)
        
        BDNF,NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 homodimer [plasma membrane] (Rattus norvegicus)
        
        NTF4:p-5Y-NTRK2 [plasma membrane] (Rattus norvegicus)
        
        NTF4 homodimer [extracellular region] (Rattus norvegicus)
        
        Ntf4 [extracellular region] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P34131 Ntf4

Gene Names

Ntf4, Nt4, Ntf5

Chain

signal peptide:1-21, propeptide:22-79, chain:80-209

Reference Genes

BioGPS Gene:25730 Ntf4

ENSEMBL:ENSRNOG00000020783.3 Ntf4

ENSEMBL:ENSRNOG00055005881 Ntf4

ENSEMBL:ENSRNOG00060008911 Ntf4

ENSEMBL:ENSRNOG00065029767 Ntf4

KEGG Gene (Rattus norvegicus):25730 Ntf4

Monarch:25730 Ntf4

NCBI Gene:25730 Ntf4

UCSC:P34131 Ntf4

Reference Transcript

RefSeq:NM_013184.3 Ntf4

Other Identifiers

10706807

1369887_at

17616315

25730

5641888

5647539

6037637

6130589

6319512

6337259

6445505

6703876

A_64_P071873

GE1224248

GO:0005102

GO:0005576

GO:0007402

GO:0007616

GO:0008052

GO:0008083

GO:0008344

GO:0008544

GO:0012501

GO:0030154

GO:0042490

GO:0043069

GO:0048018

GO:0048856

GO:0050877

GO:0060384

GO:0061193

GO:0098772

ILMN_1363013

M86742cds_s_at

Y07659exon_at

Participates

as a component of

NTF4 homodimer [extracellular region] (Rattus norvegicus)

Other forms of this molecule

Ntf4 [extracellular region]

Inferred From

NTF4 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_037316.2

Ensembl

ENSRNOP00000093109, ENSRNOT00000028194, ENSRNOG00000020783, ENSRNOT00000095694, ENSRNOP00000028195

PRO

P34131

RGD

3212