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C4 [extracellular region]
Stable Identifier
R-RNO-166734
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
extracellular region
Synonyms
C4A(20-675), P08649
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Innate Immune System (Rattus norvegicus)
Complement cascade (Rattus norvegicus)
Activation of C3 and C5 (Rattus norvegicus)
Activation of C5 (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Cleavage of C3 by C3 convertases (Rattus norvegicus)
C3 convertases [plasma membrane] (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Formation of classic pathway C5 convertase (Rattus norvegicus)
C4b:C2a:C3b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Initial triggering of complement (Rattus norvegicus)
C4b binds to cell surface (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
C4A(20-675):C4A(1454-1744):S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
C4B(1454-1744):C4B(20-675):S-(L-isoglutamyl)-L-cysteine-C4B(757-1446) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Conversion of C4 into C4a and C4b (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
C4A(20-675):C4A(1454-1744):S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
C4B(1454-1744):C4B(20-675):S-(L-isoglutamyl)-L-cysteine-C4B(757-1446) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Complement Factor 4 [extracellular region] (Rattus norvegicus)
Complement factor 4A [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Complement factor 4B [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Formation of Classical C3 convertase (C4b:C2a complex) (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Regulation of Complement cascade (Rattus norvegicus)
CD46 binds C4b (Rattus norvegicus)
CD46:Cell surface:C4b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
CD55 (DAF) binds C3bBb, C4bC2a (Rattus norvegicus)
CD55:C4bC2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
CR1 binds C3bBb/C4bC2a (Rattus norvegicus)
CR1:C4bC2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Cell surface:C4b:C2a [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Complement factor I binds to MCP, CR1:C4b, C3b (Rattus norvegicus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Rattus norvegicus)
CD46:Cell surface:C4b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
CR1:C4b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Rattus norvegicus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Rattus norvegicus)
CD46:Cell surface:C4b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
CR1:C4b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Factor I inactivates MCP/CR1-bound C4b/C3b (Rattus norvegicus)
C4c, C3f [extracellular region] (Rattus norvegicus)
C4c [extracellular region] (Rattus norvegicus)
C4A-derived C4c [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
C4B-derived C4c [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
CFI:CD46, CR1:C4b, C3b complexes [plasma membrane] (Rattus norvegicus)
CD46, CR1:C4b:C3b complexes [plasma membrane] (Rattus norvegicus)
CD46:Cell surface:C4b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
CR1:C4b [plasma membrane] (Rattus norvegicus)
Cell surface:C4b [plasma membrane] (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
Hydrolysis of internal thioester in C4b (Rattus norvegicus)
C4b [extracellular region] (Rattus norvegicus)
C4A(20-675):C4A(1454-1744):S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
C4B(1454-1744):C4B(20-675):S-(L-isoglutamyl)-L-cysteine-C4B(757-1446) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
C4b with hydrolysed thioester [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4A-derived C4b [extracellular region] (Rattus norvegicus)
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
deamidated-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4 [extracellular region] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P08649
Gene Names
C4
Reference Genes
BioGPS Gene:24233 C4
ENSEMBL:ENSRNOG00000000443
ENSEMBL:ENSRNOG00000047657
ENSEMBL:ENSRNOG00000066573
ENSEMBL:ENSRNOG00055006626
ENSEMBL:ENSRNOG00060007207
ENSEMBL:ENSRNOG00065033200
KEGG Gene (Rattus norvegicus):24233 C4
Monarch:24233 C4
NCBI Gene:24233 C4
UCSC:P08649 C4
Reference Transcript
RefSeq:NM_031504.3 C4
Participates
as a component of
deamidated-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
C4B-derived C4c [extracellular region] (Rattus norvegicus)
Complement factor 4B [extracellular region] (Rattus norvegicus)
C4B(1454-1744):C4B(20-675):S-(L-isoglutamyl)-L-cysteine-C4B(757-1446) [extracellular region] (Rattus norvegicus)
deamidated, estrer-crosslinked-Q1013-C4B-derived C4b [extracellular region] (Rattus norvegicus)
as a member of
Homologues of C4A(20-675) [extracellular region] (Rattus norvegicus)
Other forms of this molecule
phospho-C4 [endoplasmic reticulum lumen]
C4 [endoplasmic reticulum lumen]
C4 [extracellular region]
C4 [extracellular region]
C4 [plasma membrane]
C4 [extracellular region]
C4 [extracellular region]
C4 [extracellular region]
C4 [extracellular region]
C4 [extracellular region]
C4 [extracellular region]
Inferred From
C4B(20-675) [extracellular region]
(Homo sapiens)
C4A(20-675) [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_113692.2
PRO
P08649
RGD
620005
,
1591983
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