Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Tsc1 [plasma membrane]
Stable Identifier
R-RNO-165169
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
TSC1, Q9Z136
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
Formation of TSC1:TSC2 complex (Rattus norvegicus)
Tsc1 [plasma membrane] (Rattus norvegicus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)
TSC1:p-S1387-TSC2 [plasma membrane] (Rattus norvegicus)
Tsc1 [plasma membrane] (Rattus norvegicus)
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
TSC1:p-S1387-TSC2 [plasma membrane] (Rattus norvegicus)
Tsc1 [plasma membrane] (Rattus norvegicus)
Signal Transduction (Rattus norvegicus)
MTOR signalling (Rattus norvegicus)
Energy dependent regulation of mTOR by LKB1-AMPK (Rattus norvegicus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)
TSC1:p-S1387-TSC2 [plasma membrane] (Rattus norvegicus)
Tsc1 [plasma membrane] (Rattus norvegicus)
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
TSC1:p-S1387-TSC2 [plasma membrane] (Rattus norvegicus)
Tsc1 [plasma membrane] (Rattus norvegicus)
Inhibition of TSC complex formation by PKB (Rattus norvegicus)
Phosphorylation of complexed TSC2 by PKB (Rattus norvegicus)
TSC1:Inhibited TSC2-1-P [cytosol] (Rattus norvegicus)
Tsc1 [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q9Z136
Gene Names
Tsc1
Reference Genes
BioGPS Gene:60445 Tsc1
ENSEMBL:ENSRNOG00000011470
KEGG Gene (Rattus norvegicus):60445 Tsc1
Monarch:60445 Tsc1
NCBI Gene:60445 Tsc1
UCSC:Q9Z136 Tsc1
Reference Transcript
RefSeq:XM_006233844.2 Tsc1
RefSeq:XM_006233847.3 Tsc1
RefSeq:XM_006233843.2 Tsc1
RefSeq:NM_021854.1 Tsc1
RefSeq:XM_006233846.2 Tsc1
RefSeq:XM_006233845.2 Tsc1
Participates
as a component of
TSC1:Inhibited TSC2-1-P [cytosol] (Rattus norvegicus)
TSC1:p-S1387-TSC2 [plasma membrane] (Rattus norvegicus)
as an input of
Formation of TSC1:TSC2 complex (Rattus norvegicus)
Other forms of this molecule
Tsc1 [cytosol]
Inferred From
TSC1 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_068626.1
,
XP_006233909.1
,
XP_006233906.1
,
XP_006233905.1
,
XP_006233907.1
,
XP_006233908.1
PRO
Q9Z136
RGD
620124
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text