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F2 [endoplasmic reticulum lumen]
Stable Identifier
R-RNO-159800
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
endoplasmic reticulum lumen
Synonyms
10xCbxE-F2(25-622), P18292
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Rattus norvegicus)
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins (Rattus norvegicus)
Gamma-carboxylation of protein precursors (Rattus norvegicus)
GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Rattus norvegicus)
F2 [endoplasmic reticulum lumen] (Rattus norvegicus)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)
Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)
F2 [endoplasmic reticulum lumen] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P18292
Gene Names
F2
Reference Genes
ENSEMBL:ENSRNOG00000016325
ENSEMBL:ENSRNOG00055016064
ENSEMBL:ENSRNOG00060009925
ENSEMBL:ENSRNOG00065023700
UCSC:P18292 F2
Participates
as an input of
Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)
as an output of
GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Rattus norvegicus)
Other forms of this molecule
F2 [Golgi lumen]
F2 [Golgi lumen]
F2 [Golgi lumen]
F2 [endoplasmic reticulum lumen]
F2 [extracellular region]
F2 [extracellular region]
F2 [plasma membrane]
F2 [plasma membrane]
F2 [extracellular region]
F2 [extracellular region]
Inferred From
10xCbxE-F2(25-622) [endoplasmic reticulum lumen]
(Homo sapiens)
Modified Residues
Name
L-gamma-carboxyglutamic acid at 75 (in Homo sapiens)
Coordinate
75
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 72 (in Homo sapiens)
Coordinate
72
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 69 (in Homo sapiens)
Coordinate
69
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 68 (in Homo sapiens)
Coordinate
68
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 63 (in Homo sapiens)
Coordinate
63
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 62 (in Homo sapiens)
Coordinate
62
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 59 (in Homo sapiens)
Coordinate
59
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 57 (in Homo sapiens)
Coordinate
57
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 50 (in Homo sapiens)
Coordinate
50
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Name
L-gamma-carboxyglutamic acid at 49 (in Homo sapiens)
Coordinate
49
PsiMod Name
L-gamma-carboxyglutamic acid [MOD:00041]
PsiMod Definition
A protein modification that effectively converts an L-glutamic acid residue to L-gamma-carboxyglutamic acid.
Cross References
OpenTargets
ENSG00000180210
ZINC - Substances
THRB_RAT
ZINC target
P18292
PRO
P18292
ZINC - Predictions - Purchasable
THRB_RAT
RGD
61996
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