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F2 [plasma membrane]
Stable Identifier
R-RNO-140809
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
plasma membrane
Synonyms
thrombin heavy chain, P18292
Locations in the PathwayBrowser
Expand all
Hemostasis (Rattus norvegicus)
Cell surface interactions at the vascular wall (Rattus norvegicus)
Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
activated thrombin:thrombomodulin [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
Formation of Fibrin Clot (Clotting Cascade) (Rattus norvegicus)
Common Pathway of Fibrin Clot Formation (Rattus norvegicus)
Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
activated thrombin:thrombomodulin [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Rattus norvegicus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Rattus norvegicus)
thrombin:SERPINC1:SERPINC1 activators [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin (Rattus norvegicus)
activated thrombin:thrombomodulin [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Rattus norvegicus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
thrombin:SERPINC1:SERPINC1 activators [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
thrombin:cleaved SERPINC1:SERPINC1 activators [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators (Rattus norvegicus)
thrombin:cleaved SERPINC1:SERPINC1 activators [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
Intrinsic Pathway of Fibrin Clot Formation (Rattus norvegicus)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Rattus norvegicus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
F2 [plasma membrane] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:P18292
Gene Names
F2
Reference Genes
ENSEMBL:ENSRNOG00000016325
ENSEMBL:ENSRNOG00055016064
ENSEMBL:ENSRNOG00060009925
ENSEMBL:ENSRNOG00065023700
UCSC:P18292 F2
Participates
as a component of
activated thrombin (factor IIa) [plasma membrane] (Rattus norvegicus)
Other forms of this molecule
F2 [Golgi lumen]
F2 [Golgi lumen]
F2 [Golgi lumen]
F2 [endoplasmic reticulum lumen]
F2 [endoplasmic reticulum lumen]
F2 [extracellular region]
F2 [extracellular region]
F2 [plasma membrane]
F2 [extracellular region]
F2 [extracellular region]
Inferred From
thrombin heavy chain [plasma membrane]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000180210
ZINC - Substances
THRB_RAT
ZINC target
P18292
PRO
P18292
ZINC - Predictions - Purchasable
THRB_RAT
RGD
61996
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