Reactome | Pf4 [extracellular region]

Pf4 [extracellular region]

Stable Identifier

R-RNO-114629

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

extracellular region

Synonyms

PF4(48-101), P06765

Locations in the PathwayBrowser

Expand all

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR downstream signalling (Rattus norvegicus)
    - G alpha (i) signalling events (Rattus norvegicus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Rattus norvegicus)
        
        CXCR2 ligands [extracellular region] (Rattus norvegicus)
        
        CXCL4 homotetramer [extracellular region] (Rattus norvegicus)
        
        Pf4 [extracellular region] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Rattus norvegicus)
        
        CXCR2 ligands [extracellular region] (Rattus norvegicus)
        
        CXCL4 homotetramer [extracellular region] (Rattus norvegicus)
        
        Pf4 [extracellular region] (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Chemokine receptors bind chemokines (Rattus norvegicus)
        
        Receptor CXCR2 binds ligands CXCL1 to 7 (Rattus norvegicus)
        
        CXCR2 ligands [extracellular region] (Rattus norvegicus)
        
        CXCL4 homotetramer [extracellular region] (Rattus norvegicus)
        
        Pf4 [extracellular region] (Rattus norvegicus)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Rattus norvegicus)
        
        CXCR2 ligands [extracellular region] (Rattus norvegicus)
        
        CXCL4 homotetramer [extracellular region] (Rattus norvegicus)
        
        Pf4 [extracellular region] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:P06765

Gene Names

Pf4

Reference Genes

BioGPS Gene:360918 Pf4

ENSEMBL:ENSRNOG00000028015

KEGG:rno:360918 Pf4

Monarch:360918 Pf4

NCBI Gene:360918 Pf4

UCSC:P06765 Pf4

Reference Transcript

RefSeq:NM_001007729.2 Pf4

Other Identifiers

10775914

1371250_at

17693479

360918

5928322

6258893

6658746

6678938

6724099

A_42_P508984

GE1259513

GO:0002376

GO:0005576

GO:0006935

GO:0006952

GO:0006955

GO:0008009

GO:0042832

GO:0048018

GO:0061844

GO:0098542

GO:0098772

ILMN_1369599

PH_rn_0015396

rc_AI169104_at

Participates

as a member of

Platelet alpha granule contents [extracellular region] (Rattus norvegicus)

as a component of

CXCL4 homotetramer [extracellular region] (Rattus norvegicus)

Other forms of this molecule

Pf4 [extracellular region]

Pf4 [platelet alpha granule lumen]

Inferred From

PF4(48-101) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001007730.1

ENSEMBL

ENSRNOG00000028015, ENSRNOT00000033406, ENSRNOP00000032276

PRO

P06765

GlyGen

P06765

RGD

3305