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IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]
Stable Identifier
R-RNO-1067690
Type
Complex
Species
Rattus norvegicus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Rattus norvegicus)
Cytokine Signaling in Immune system (Rattus norvegicus)
Signaling by Interleukins (Rattus norvegicus)
Interleukin-12 family signaling (Rattus norvegicus)
Interleukin-27 signaling (Rattus norvegicus)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Rattus norvegicus)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Interleukin-35 Signalling (Rattus norvegicus)
IL35 binds IL-12RB2:IL6ST receptor (Rattus norvegicus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL35 binds IL6ST:IL6ST receptor (Rattus norvegicus)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Rattus norvegicus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Rattus norvegicus)
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Interleukin-6 family signaling (Rattus norvegicus)
IL-6-type cytokine receptor ligand interactions (Rattus norvegicus)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
LIFR:JAKs bind gp130:JAKs:CNTFR (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:gp130:JAKs:LIFR:JAKs [plasma membrane] (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
gp130:JAKs bind CNTFR (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
Interleukin-6 signaling (Rattus norvegicus)
Assembly of hexameric IL-6 receptor (Rattus norvegicus)
IL6 receptor hexamer:JAKs [plasma membrane] (Rattus norvegicus)
IL6 receptor trimer:JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6 receptor trimer:JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
JAK activation (Rattus norvegicus)
IL6 receptor hexamer:JAKs [plasma membrane] (Rattus norvegicus)
IL6 receptor trimer:JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Il6st [plasma membrane]
(Rattus norvegicus)
JAK1, JAK2, (TYK2) [cytosol]
(Rattus norvegicus)
Participates
as an input of
IL35 binds IL6ST:IL6ST receptor (Rattus norvegicus)
IL35 binds IL-12RB2:IL6ST receptor (Rattus norvegicus)
IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)
gp130:JAKs bind CNTFR (Rattus norvegicus)
IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)
IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Rattus norvegicus)
as a component of
IL-35:(IL6ST:JAK1:JAK2) dimer [plasma membrane] (Rattus norvegicus)
IL35:IL6ST:JAK1:IL12RB2:JAK2 [plasma membrane] (Rattus norvegicus)
IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] (Rattus norvegicus)
IL6RA:IL6:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Rattus norvegicus)
IL6:sIL6R:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
IL6:IL6RA:IL6RB:JAKs [plasma membrane] (Rattus norvegicus)
Inferred From
IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]
(Homo sapiens)
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