Reactome | phospho-p-T200-CAMK4 [nucleoplasm]

phospho-p-T200-CAMK4 [nucleoplasm]

Stable Identifier

R-PFA-9619155

Type

Protein [EntityWithAccessionedSequence]

Species

Plasmodium falciparum

Compartment

nucleoplasm

Synonyms

Q8I534

Locations in the PathwayBrowser

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Neuronal System (Plasmodium falciparum)

- Transmission across Chemical Synapses (Plasmodium falciparum)
  - Neurotransmitter receptors and postsynaptic signal transmission (Plasmodium falciparum)
    - Activation of NMDA receptors and postsynaptic events (Plasmodium falciparum)
      - Post NMDA receptor activation events (Plasmodium falciparum)
        
        CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Plasmodium falciparum)
        
        CAMK4 autophosphorylates (Plasmodium falciparum)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Plasmodium falciparum)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Plasmodium falciparum)

Signal Transduction (Plasmodium falciparum)

- Intracellular signaling by second messengers (Plasmodium falciparum)
  - DAG and IP3 signaling (Plasmodium falciparum)
    - CaM pathway (Plasmodium falciparum)
      - Calmodulin induced events (Plasmodium falciparum)
        
        CaMK IV-mediated phosphorylation of CREB (Plasmodium falciparum)
        
        CAMK4 autophosphorylates (Plasmodium falciparum)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Plasmodium falciparum)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Plasmodium falciparum)
- Signaling by GPCR (Plasmodium falciparum)
  - GPCR downstream signalling (Plasmodium falciparum)
    - G alpha (i) signalling events (Plasmodium falciparum)
      - Opioid Signalling (Plasmodium falciparum)
        
        G-protein mediated events (Plasmodium falciparum)
        
        PLC beta mediated events (Plasmodium falciparum)
        
        Ca-dependent events (Plasmodium falciparum)
        
        CaM pathway (Plasmodium falciparum)
        
        Calmodulin induced events (Plasmodium falciparum)
        
        CaMK IV-mediated phosphorylation of CREB (Plasmodium falciparum)
        
        CAMK4 autophosphorylates (Plasmodium falciparum)
        
        p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Plasmodium falciparum)
        
        phospho-p-T200-CAMK4 [nucleoplasm] (Plasmodium falciparum)

External Reference Information

External Reference

UniProt:Q8I534

Reference Genes

BioGPS Gene:811429

ENSEMBL:PF3D7_1238900

KEGG Gene (Plasmodium falciparum):PF3D7_1238900

Monarch:811429

NCBI Gene:811429

PlasmoDB:PF3D7_1238900

Reference Transcript

RefSeq:XM_001350747.1

Participates

as a component of

p-T200-CAMK4:CALM1:4xCa2+ [nucleoplasm] (Plasmodium falciparum)

Other forms of this molecule

phospho-p-S12,S13,T200-CAMK4 [nucleoplasm]

Inferred From

p-T200-CAMK4 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 200 (in Homo sapiens)

Coordinate

200

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

XP_001350783.1

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