Reactome | RPL26 [cytosol]

RPL26 [cytosol]

Stable Identifier

R-PFA-72436

Type

Protein [EntityWithAccessionedSequence]

Species

Plasmodium falciparum

Compartment

cytosol

Synonyms

O77364

Locations in the PathwayBrowser

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Metabolism of RNA (Plasmodium falciparum)

- Nonsense-Mediated Decay (NMD) (Plasmodium falciparum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Plasmodium falciparum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        60S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPL26 [cytosol] (Plasmodium falciparum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        60S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPL26 [cytosol] (Plasmodium falciparum)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Plasmodium falciparum)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Plasmodium falciparum)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        60S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPL26 [cytosol] (Plasmodium falciparum)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        60S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPL26 [cytosol] (Plasmodium falciparum)

External Reference Information

External Reference

UniProt:O77364

Reference Genes

BioGPS Gene:814443

ENSEMBL:PF3D7_0312800

KEGG Gene (Plasmodium falciparum):PF3D7_0312800

Monarch:814443

NCBI Gene:814443

PlasmoDB:PF3D7_0312800

Reference Transcript

RefSeq:XM_001351163.1

Participates

as a component of

Inferred From

RPL26,RPL26L1 [cytosol] (Homo sapiens)

RPL26 [cytosol] (Homo sapiens)

RPL26L1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_001351199.1

PDB

3JBP, 5UMD, 3JBN, 3JBO, 3J79