Reactome | RPS5 [cytosol]

RPS5 [cytosol]

Stable Identifier

R-PFA-72379

Type

Protein [EntityWithAccessionedSequence]

Species

Plasmodium falciparum

Compartment

cytosol

Synonyms

Q8IBN5

Locations in the PathwayBrowser

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Metabolism of RNA (Plasmodium falciparum)

- Nonsense-Mediated Decay (NMD) (Plasmodium falciparum)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Plasmodium falciparum)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        40S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPS5 [cytosol] (Plasmodium falciparum)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        40S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPS5 [cytosol] (Plasmodium falciparum)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Plasmodium falciparum)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Plasmodium falciparum)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        40S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPS5 [cytosol] (Plasmodium falciparum)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Plasmodium falciparum)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Plasmodium falciparum)
        
        80S ribosome [cytosol] (Plasmodium falciparum)
        
        40S ribosomal complex [cytosol] (Plasmodium falciparum)
        
        RPS5 [cytosol] (Plasmodium falciparum)

External Reference Information

External Reference

UniProt:Q8IBN5

Reference Genes

BioGPS Gene:2655132

ENSEMBL:PF3D7_0721600

KEGG Gene (Plasmodium falciparum):PF3D7_0721600

Monarch:2655132

NCBI Gene:2655132

PlasmoDB:PF3D7_0721600

Reference Transcript

RefSeq:XM_001349082.1

Participates

as a component of

40S ribosomal complex [cytosol] (Plasmodium falciparum)

Other forms of this molecule

RPS5 [nucleoplasm]

Inferred From

RPS5 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_001349118.1

PDB

3JBO, 6OKK, 3J7A, 3JBP, 3JBN

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