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phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
Stable Identifier
R-PFA-5672664
Type
Protein [EntityWithAccessionedSequence]
Species
Plasmodium falciparum
Compartment
cytosol
Synonyms
C6KT74
Locations in the PathwayBrowser
Expand all
Signal Transduction (Plasmodium falciparum)
MAPK family signaling cascades (Plasmodium falciparum)
MAPK1/MAPK3 signaling (Plasmodium falciparum)
RAF/MAP kinase cascade (Plasmodium falciparum)
Negative regulation of MAPK pathway (Plasmodium falciparum)
PEBP1 binds activated RAF1 (Plasmodium falciparum)
p21 RAS:GTP:activated RAF1 homo/heterodimer:PEBP1 [plasma membrane] (Plasmodium falciparum)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Plasmodium falciparum)
'activator' RAFs [cytosol] (Plasmodium falciparum)
Homologues of p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Plasmodium falciparum)
'activator' RAFs [cytosol] (Plasmodium falciparum)
Homologues of p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
PP5 dephosphorylates RAF1 S338 (Plasmodium falciparum)
p21RAS:GTP:activated RAF1 homo/heterodimer [plasma membrane] (Plasmodium falciparum)
'activator' RAFs [cytosol] (Plasmodium falciparum)
Homologues of p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
p21RAS:GTP:dephosphorylated RAF1 homo/heterodimer [plasma membrane] (Plasmodium falciparum)
'activator' RAFs [cytosol] (Plasmodium falciparum)
Homologues of p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
RAF activation (Plasmodium falciparum)
Raf dimer inhibitors bind RAF heterodimers (Plasmodium falciparum)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Plasmodium falciparum)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Plasmodium falciparum)
'activator' RAF:YWHAB dimer [cytosol] (Plasmodium falciparum)
'activator' RAFs [cytosol] (Plasmodium falciparum)
Homologues of p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Plasmodium falciparum)
p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Plasmodium falciparum)
p21 RAS:GTP:'activator' RAF:YWHAB dimer [plasma membrane] (Plasmodium falciparum)
'activator' RAF:YWHAB dimer [cytosol] (Plasmodium falciparum)
'activator' RAFs [cytosol] (Plasmodium falciparum)
Homologues of p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
External Reference Information
External Reference
UniProt:C6KT74
Reference Genes
BioGPS Gene:3885874
ENSEMBL:PF3D7_0623800
KEGG Gene (Plasmodium falciparum):PF3D7_0623800
Monarch:3885874
NCBI Gene:3885874
PlasmoDB:PF3D7_0623800
Reference Transcript
RefSeq:XM_961127.1
Participates
as a member of
Homologues of p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (Plasmodium falciparum)
Other forms of this molecule
phospho-hyperphosphorylated BRAF [plasma membrane]
phospho-hyperphosphorylated RAF1 [plasma membrane]
phospho-p-S299,S302,T452,T455,S582 ARAF [cytosol]
phospho-p-S446,T599,S602,S729 BRAF [cytosol]
phospho-p-S446,S729-BRAF [cytosol]
phospho-p-S446,T599,S602,S729 BRAF [plasma membrane]
phospho-p-S299,S302,T452,T455,S582 ARAF [plasma membrane]
phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
phospho-p-S582 ARAF [cytosol]
phospho-p-S621-RAF1 [cytosol]
RIPK2 [cytosol]
RAF1 [cytosol]
RIPK1 [cytosol]
K63polyUb-RIPK1 [cytosol]
phospho-p-S214,S582 ARAF [cytosol]
phospho-p-S259,S621-RAF1 [cytosol]
phospho-p-S365,S446,S729 BRAF [cytosol]
phospho-p-Y341,T491,S494,S621 RAF1 [plasma membrane]
phospho-p-S621-RAF1 [plasma membrane]
Inferred From
p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 621 (in Homo sapiens)
Coordinate
621
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 341 (in Homo sapiens)
Coordinate
341
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-serine at 338 (in Homo sapiens)
Coordinate
338
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 491 (in Homo sapiens)
Coordinate
491
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 494 (in Homo sapiens)
Coordinate
494
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_966220.1
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