Reactome | COPA [cytosol]

COPA [cytosol]

Stable Identifier

R-PFA-199978

Type

Protein [EntityWithAccessionedSequence]

Species

Plasmodium falciparum

Compartment

cytosol

Synonyms

C6KSR5

Locations in the PathwayBrowser

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Metabolism of proteins (Plasmodium falciparum)

- Post-translational protein modification (Plasmodium falciparum)
  - Asparagine N-linked glycosylation (Plasmodium falciparum)
    - Transport to the Golgi and subsequent modification (Plasmodium falciparum)
      - ER to Golgi Anterograde Transport (Plasmodium falciparum)
        
        COPI-mediated anterograde transport (Plasmodium falciparum)
        
        Active ARF recruits coatomer (Plasmodium falciparum)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)

Vesicle-mediated transport (Plasmodium falciparum)

- Membrane Trafficking (Plasmodium falciparum)
  - ER to Golgi Anterograde Transport (Plasmodium falciparum)
    - COPI-mediated anterograde transport (Plasmodium falciparum)
      - Active ARF recruits coatomer (Plasmodium falciparum)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Plasmodium falciparum)
    - Golgi-to-ER retrograde transport (Plasmodium falciparum)
      - COPI-dependent Golgi-to-ER retrograde traffic (Plasmodium falciparum)
        
        ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Plasmodium falciparum)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Plasmodium falciparum)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)
        
        ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Plasmodium falciparum)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Plasmodium falciparum)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)
        
        Active ARF recruits coatomer to the Golgi (Plasmodium falciparum)
        
        RAB1:GTP:GBF1:ARF:GTP:coatomer [Golgi membrane] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)
        
        coatomer [cytosol] (Plasmodium falciparum)
        
        trimeric coatomer complex [cytosol] (Plasmodium falciparum)
        
        COPA [cytosol] (Plasmodium falciparum)

External Reference Information

External Reference

UniProt:C6KSR5

Reference Genes

BioGPS Gene:3885883

ENSEMBL:PF3D7_0606700

KEGG Gene (Plasmodium falciparum 3D7):PF3D7_0606700

Monarch:3885883

NCBI Gene:3885883

PlasmoDB:PF3D7_0606700

Reference Transcript

RefSeq:XM_960964.2

Participates

as a component of

trimeric coatomer complex [cytosol] (Plasmodium falciparum)

Other forms of this molecule

COPA [transport vesicle]

Inferred From

COPA [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_966057.2