Reactome | Homologues of p-T218,Y220-MAPK7 [nucleoplasm]

Homologues of p-T218,Y220-MAPK7 [nucleoplasm]

Stable Identifier

R-PFA-198738-3

Type

Set [DefinedSet]

Species

Plasmodium falciparum

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Immune System (Plasmodium falciparum)

- Cytokine Signaling in Immune system (Plasmodium falciparum)
  - Signaling by Interleukins (Plasmodium falciparum)
    - Interleukin-17 signaling (Plasmodium falciparum)
      - MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
- Innate Immune System (Plasmodium falciparum)
  - Toll-like Receptor Cascades (Plasmodium falciparum)
    - Toll Like Receptor 10 (TLR10) Cascade (Plasmodium falciparum)
      - MyD88 cascade initiated on plasma membrane (Plasmodium falciparum)
        
        MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
    - Toll Like Receptor 2 (TLR2) Cascade (Plasmodium falciparum)
      - Toll Like Receptor TLR1:TLR2 Cascade (Plasmodium falciparum)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Plasmodium falciparum)
        
        MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
      - Toll Like Receptor TLR6:TLR2 Cascade (Plasmodium falciparum)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Plasmodium falciparum)
        
        MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
    - Toll Like Receptor 3 (TLR3) Cascade (Plasmodium falciparum)
      - MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
    - Toll Like Receptor 4 (TLR4) Cascade (Plasmodium falciparum)
      - MyD88-independent TLR4 cascade (Plasmodium falciparum)
        
        TRIF(TICAM1)-mediated TLR4 signaling (Plasmodium falciparum)
        
        MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Plasmodium falciparum)
        
        MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
    - Toll Like Receptor 5 (TLR5) Cascade (Plasmodium falciparum)
      - MyD88 cascade initiated on plasma membrane (Plasmodium falciparum)
        
        MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Plasmodium falciparum)
      - MyD88 dependent cascade initiated on endosome (Plasmodium falciparum)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Plasmodium falciparum)
        
        MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)
    - Toll Like Receptor 9 (TLR9) Cascade (Plasmodium falciparum)
      - MyD88 dependent cascade initiated on endosome (Plasmodium falciparum)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Plasmodium falciparum)
        
        MAP kinase activation (Plasmodium falciparum)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Plasmodium falciparum)
        
        ERK/MAPK targets (Plasmodium falciparum)
        
        ERKs are inactivated (Plasmodium falciparum)
        
        ERKs are inactivated by dual-specific phosphatases (DUSPs) (Plasmodium falciparum)
        
        p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Plasmodium falciparum)
        
        p-T1218, Y220 MAPK7 dimer [nucleoplasm] (Plasmodium falciparum)
        
        Homologues of p-T218,Y220-MAPK7 [nucleoplasm] (Plasmodium falciparum)

Participants

members

Participant Of

output

ERK5 translocates to the nucleus

hasComponent

p-T1218, Y220 MAPK7 dimer [nucleoplasm]

Inferred From

p-T218,Y220-MAPK7 [nucleoplasm] (Homo sapiens)

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