MAPK1 phosphorylates Rps6ka1

Stable Identifier
R-NUL-9619973
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
MAPK1 phosphorylates Rps6ka1
Recombinant human MAPK1 (ERK2) phosphorylates recombinant rat Rps6ka1 on threonine residue T359, serine residue S363 and threonine residue T573 (Dalby et al. 1998).
Literature References
PubMed ID Title Journal Year
9430688 Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

Cohen, P, Morrice, N, Caudwell, FB, Avruch, J, Dalby, KN

J. Biol. Chem. 1998
Participants
Input
Output
Catalyst Activity

protein serine/threonine kinase activity of p-T185,Y187 MAPK1 dimer [cytosol]

Physical Entity
p-T185,Y187 MAPK1 dimer [cytosol] (Homo sapiens)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
ERKs phosphorylate RSKs (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-10)
Reviewed
Hansen, KB  (2018-11-02)
Yi, F  (2018-11-02)
Created
Orlic-Milacic, M  (2018-09-19)
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