RAN:GTP binds transportin associated with Nup107-160 and displaces Nup107-160

Stable Identifier
R-NUL-9616174
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
RAN:GTP binds transportin associated with Nup107-160 and displaces Nup107-160
Recombinant human RAN:GTP binds to recombinant human transportin (TNPO1) associated with the Xenopus Nup107-160 complex and displaces Nup107-160 (Lau et al. 2009).
Literature References
PubMed ID Title Journal Year
19641022 Transportin regulates major mitotic assembly events: from spindle to nuclear pore assembly

Lau, CK, Forbes, DJ, Rasala, BA, Chan, RC, Delmar, VA, Fichtman, B, Bernis, C, Phung, Q

Mol. Biol. Cell 2009
Participants
Input
Output
Orthologous Events
RAN:GTP binds TNPO1/KPNB1 (transportin/importin beta) associated with the Nup107-160 complex and releases Nup107-160 (Homo sapiens)
Authored
Orlic-Milacic, M  (2019-11-26)
Reviewed
Gerace, L  (2019-11-07)
Created
Orlic-Milacic, M  (2018-08-09)
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