HES5 gene transcription is stimulated by Notch4

Stable Identifier
R-NUL-9604449
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
General
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HES5 gene transcription is stimulated by Notch4

Recombinant mouse Notch4 intracellular domain fragment (NICD4), in complex with recombinant human RBPJ (CSL) and one of recombinant human mastermind proteins, MAML1, MAML2 or MAML3, stimulates transcription from the human HES5 promoter-luciferase reporter construct (Lin et al. 2002).

Literature References
PubMed ID Title Journal Year
12386158 Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling

Lin, SE, Oyama, T, Nagase, T, Harigaya, K, Kitagawa, M

J. Biol. Chem. 2002
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