BDNF- or NTF4-activated Ntrk2 binds Shc1

Stable Identifier
R-NUL-9030473
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
BDNF- or NTF4-activated Ntrk2 binds Shc1

Mouse Ntrk2, activated by recombinant human BDNF or NTF4 (NT-4), binds Shc1 isoforms p52 (Shc-1) and p47 (Shc1-3) (Minichiello et al. 1998).

Literature References
PubMed ID Title Journal Year
9728915 Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses

Minichiello, L, Casagranda, F, Tatche, RS, Stucky, CL, Postigo, A, Lewin, GR, Davies, AM, Klein, R

Neuron 1998
Participants
Orthologous Events
Authored
Reviewed
Created