cGAS ligands [cytosol]

Stable Identifier
Set [DefinedSet]
Human immunodeficiency virus 1
GO Cellular Component
host cell cytosol (0044164)
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
23929945 Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

Gao, D, Wu, J, Wu, YT, Du, F, Aroh, C, Yan, N, Sun, L, Chen, ZJ

Science 2013
23258412 Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA

Wu, J, Sun, L, Chen, X, Du, F, Shi, H, Chen, C, Chen, ZJ

Science 2013
25730264 A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis

Dey, B, Dey, RJ, Cheung, LS, Pokkali, S, Guo, H, Lee, JH, Bishai, WR

Nat. Med. 2015
26048136 The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

Watson, RO, Bell, SL, MacDuff, DA, Kimmey, JM, Diner, EJ, Olivas, J, Vance, RE, Stallings, CL, Virgin, HW, Cox, JS

Cell Host Microbe 2015
24970844 Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway

Hansen, K, Prabakaran, T, Laustsen, A, Jørgensen, SE, Rahbæk, SH, Jensen, SB, Nielsen, R, Leber, JH, Decker, T, Horan, KA, Jakobsen, MR, Paludan, SR

EMBO J. 2014
Name Identifier Synonyms
viral infectious disease DOID:934 Viral disease, virus infection, virus infection
bacterial infectious disease DOID:104
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