Cdk5:p25 phosphorylates FOXO3

Stable Identifier
R-NUL-8870566
Type
Reaction [transition]
Species
Homo sapiens
Compartment
General
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Cdk5:p25 phosphorylates FOXO3

Recombinant mouse Cdk5 in complex with recombinant mouse p25 phosphorylates recombinant human FOXO3 on serine residues S43, S173, S294 and S325 (Shi et al. 2016).

Literature References
PubMed ID Title Journal Year
26962010 Cdk5-FOXO3a axis: initially neuroprotective, eventually neurodegenerative in Alzheimer's disease models

Shi, C, Viccaro, K, Lee, HG, Shah, K

J. Cell. Sci. 2016
Participants
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of Cdk5:p25 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Created