Activated Cit phosphorylates MRLCs of myosin II complex

Stable Identifier
R-NUL-5671959
Type
Reaction [transition]
Species
Bos taurus
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Activated Cit phosphorylates MRLCs of myosin II complex
Phosphorylation of myosin regulatory light chains (MRLCs) of the myosin II complex by citron kinase was demonstrated by using a recombinant mouse Cit and a purified bovine myosin II complex (Yamashiro et al. 2003).
Literature References
PubMed ID Title Journal Year
12802051 Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II

Narumiya, S, Sasaki, Y, Totsukawa, G, Matsumura, F, Yamashiro, S, Ishizaki, T, Madaule, P, Yamakita, Y

Mol. Biol. Cell 2003
Participants
Input
Output
Catalyst Activity

protein serine/threonine kinase activity of Cit [cytosol]

Physical Entity
Cit [cytosol] (Mus musculus)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
Activated CIT phosphorylates MRLCs (Homo sapiens)
Authored
Orlic-Milacic, M  (2014-10-24)
Rivero Crespo, F  (2014-12-26)
Created
Orlic-Milacic, M  (2015-02-03)
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