WASP/N-WASP activate the Arp2/3 complex

Stable Identifier
R-NUL-442561
Type
Reaction [binding]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
WASP/N-WASP activate the Arp2/3 complex

The binding of the ARP2/3 complex to CDC42:GTP-activated N-WASP was demonstrated using rat Cdc42 and N-Wasp and bovine ARP2/3 complex (Rohatgi et al. 1999, Kiselar et al. 2007, Padrick et al. 2011).

Literature References
PubMed ID Title Journal Year
10219243 The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

Rohatgi, R, Ma, L, Miki, H, Lopez, M, Kirchhausen, Tomas, Takenawa, T, Kirschner, MW

Cell 1999
21676863 Arp2/3 complex is bound and activated by two WASP proteins

Padrick, SB, Doolittle, LK, Brautigam, CA, King, DS, Rosen, MK

Proc Natl Acad Sci U S A 2011
17251352 Visualizing Arp2/3 complex activation mediated by binding of ATP and WASp using structural mass spectrometry

Kiselar, JG, Mahaffy, R, Pollard, TD, Almo, SC, Chance, MR

Proc Natl Acad Sci U S A 2007
Participants
Orthologous Events
Authored
Reviewed
Created
Cite Us!