Smad7:SMURF1 binds phosphorylated TGFBR1

Stable Identifier
R-NUL-2169036
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
Smad7:SMURF1 binds phosphorylated TGFBR1

Smad7 recruits SMURF1 to TGF-beta (TGFB1)-activated TGF-beta receptor complex. In this study, recombinant mouse Smad7 and recombinant human SMURF1, TGFBR2 and TGFBR1 were exogenously expressed in COS7 cells (Ebisawa et al. 2001).

Literature References
PubMed ID Title Journal Year
11278251 Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

Ebisawa, T, Fukuchi, M, Murakami, G, Chiba, T, Tanaka, K, Imamura, T, Miyazono, K

J Biol Chem 2001
Participants
Orthologous Events
Authored
Reviewed
Created
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