Smad7:SMURF1 complex binds XPO1 (CRM1)

Stable Identifier
R-NUL-2169012
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
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Smad7:SMURF1 complex binds XPO1 (CRM1)

Smad7:SMURF1 complex, formed by exogenous expression of recombinant human SMURF1 and recombinant mouse Smad7 in COS7 cells, binds to XPO1 (CRM1). Recombinant XPO1 was also exogenously expressed in COS7 cells, and since the species origin of XPO1 is not specified in the paper by Tajima et al., it is assumed that XPO1 is of human origin (Tajima et al. 2003).

Literature References
PubMed ID Title Journal Year
12519765 Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

Tajima, Y, Goto, K, Yoshida, M, Shinomiya, K, Sekimoto, T, Yoneda, Y, Miyazono, K, Imamura, T

J Biol Chem 2003
Participants
Orthologous Events
Authored
Reviewed
Created