SREBP2:SCAP:CopII Coat [endoplasmic reticulum membrane]

Stable Identifier
R-NUL-1655768
Type
Complex
Species
Cricetulus griseus
Compartment
Literature References
PubMed ID Title Journal Year
17428919 Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins

Sun, LP, Seemann, J, Goldstein, JL, Brown, MS

Proc Natl Acad Sci U S A 2007
12842885 Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs

Dobrosotskaya, IY, Goldstein, JL, Brown, MS, Rawson, RB

J Biol Chem 2003
15899885 Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro

Sun, LP, Li, L, Goldstein, JL, Brown, MS

J Biol Chem 2005
12193656 Sterols block binding of COPII proteins to SCAP, thereby controlling SCAP sorting in ER

Espenshade, PJ, Li, WP, Yabe, D

Proc Natl Acad Sci U S A 2002
Participants
Participant Of
Inferred To