Plcg1 phosphorylation by P-ERBB2:P-EGFR

Stable Identifier
R-NUL-1251929
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Plcg1 phosphorylation by P-ERBB2:P-EGFR
Mouse phospholipase C gamma 1 is phosphorylated by human recombinant ERBB2 exogenously expressed in mouse fibroblasts.
Literature References
PubMed ID Title Journal Year
1672440 The erbB-2 mitogenic signaling pathway: tyrosine phosphorylation of phospholipase C-gamma and GTPase-activating protein does not correlate with erbB-2 mitogenic potency

Di Fiore, PP, Rhee, SG, Kim, UH, Fazioli, F, Segatto, O, Molloy, CJ

Mol Cell Biol 1991
Participants
Input
Output
Catalyst Activity

protein tyrosine kinase activity of Plcg1:P-ERBB2:P-EGFR [plasma membrane]

Physical Entity
Plcg1:P-ERBB2:P-EGFR [plasma membrane] (Homo sapiens)
Activity
protein tyrosine kinase activity (GO:0004713)
Orthologous Events
PLCG1 phosphorylation by p-EGFR:p-ERBB2 (Homo sapiens)
Authored
Orlic-Milacic, M  (2011-11-04)
Reviewed
Neckers, LM  (2011-11-11)
Xu, W  (2011-11-11)
Created
Orlic-Milacic, M  (2011-04-25)
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