Dehydratation of DHQ yields DHS

Stable Identifier
R-MTU-964851
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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Dehydratation of DHQ yields DHS
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AroQ, which catalyzes the dehydratation of 3-dehydroquinate (DHQ) to 3-dehydroshikimate (DHS), is a type II DHQ dehydratase. Unlike fungi DHQ dehydratases, AroQ doesn't take part in catabolism reactions (Moore et al, 1992).
Literature References
PubMed ID Title Journal Year
1329726 Inducible overproduction of the Aspergillus nidulans pentafunctional AROM protein and the type-I and -II 3-dehydroquinases from Salmonella typhi and Mycobacterium tuberculosis

Moore, JD, Lamb, HK, Garbe, T, Servos, S, Dougan, G, Charles, IG, Hawkins, AR

Biochem J 1992
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Catalyst Activity

3-dehydroquinate dehydratase activity of AroQ dodecamer [cytosol]

Physical Entity
AroQ dodecamer [cytosol] (Mycobacterium tuberculosis)
Activity
3-dehydroquinate dehydratase activity (GO:0003855)
Authored
Stephan, R  (2010-09-13)
Reviewed
Warner, D  (2010-11-25)
Matthews, L  (2025-08-22)
Created
Jassal, B  (2010-09-20)
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