deacetylation of O-acetylserine and sulfhydrylation using CysK1

Stable Identifier
R-MTU-936642
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
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Sulfhydrylation of O-acetylserine (OAS) is a four step process, as was shown with CysK1, consisting of 1) addition of OAS to pyridoxal phosphate, 2) deacetylation, 3) sulfhydrylation and 4) cleavage of cysteine. It remains to be shown that the enzyme binds to CysE, resulting in a bifunctional complex. Activity of CysK1 is not essential for M. tuberculosis (Schnell et al, 2007).

Participants
Participates
Catalyst Activity

cysteine synthase activity of CysK1 dimer [cytosol]

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