acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate

Stable Identifier
R-MTU-879298
Type
Reaction [transition]
Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate
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MshA catalyzes the transfer of acetylglucosamine from UDP-GlcNAc onto inositol-1-phosphate. From biochemical and crystal studies, there is an absolute requirement for the phosphate as substrate (Newton et al, 2006; Vetting, 2008).
Literature References
PubMed ID Title Journal Year
16940050 Biochemistry of the initial steps of mycothiol biosynthesis

Bzymek, KP, Ta, P, Newton, GL, Fahey, RC

J Biol Chem 2006
18390549 Structural and enzymatic analysis of MshA from Corynebacterium glutamicum: substrate-assisted catalysis

Frantom, PA, Vetting, MW, Blanchard, JS

J Biol Chem 2008
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Catalyst Activity

acetylglucosaminyltransferase activity of MshA [cytosol]

Physical Entity
MshA [cytosol] (Mycobacterium tuberculosis)
Activity
acetylglucosaminyltransferase activity (GO:0008375)
Authored
Stephan, R  (2010-06-07)
Reviewed
Warner, D  (2010-11-25)
Created
Stephan, R  (2010-06-16)
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