Expression of Jag1 during nephron development

Stable Identifier
R-MMU-9832188
Type
Reaction [omitted]
Species
Mus musculus
Compartment
nucleoplasm, plasma membrane
ReviewStatus
3/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of Jag1 during nephron development
Jag1 is initially expressed in the distal region of renal vesicles then Hnf1b, possibly acting via Dll1 and Notch signaling, maintains Jag1 expression in the distal region of comma-shaped bodies and in the proximal region of S-shaped bodies (Heliot et al. 2013).
Literature References
PubMed ID Title Journal Year
23362348 HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2

Heliot, C, Desgrange, A, Buisson, I, Prunskaite-Hyyryläinen, R, Shan, J, Vainio, S, Umbhauer, M, Cereghini, S

Development 2013
Participants
Input
Output
This event is regulated
Positively by
Regulator
Hnf1b [nucleoplasm] (Mus musculus)
Orthologous Events
Expression of JAG1 during nephron development (Homo sapiens)
Authored
May, B  (2023-03-28)
Created
May, B  (2023-03-29)
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