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Lhx1 binds the Npnt gene
Stable Identifier
R-MMU-9830659
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
3/5
General
SBML
|
BioPAX
Level 2
Level 3
|
PDF
SVG
|
PNG
Low
Medium
High
|
PPTX
|
SBGN
Lhx1 (also called Lim1) binds three sites near the coding region of the Nephronectin (Npnt) gene: one site is about 14 kb upstream of the transcription start and two sites are in the 3' untranslated region (Boualia et al. 2013). Loss of Lhx1 results in complete loss of Npnt expression (Boualia et al. 2013).
Literature References
PubMed ID
Title
Journal
Year
23920117
A core transcriptional network composed of Pax2/8, Gata3 and Lim1 regulates key players of pro/mesonephros morphogenesis
Tremblay, M
,
Kania, A
,
Boualia, SK
,
Bouchard, M
,
Sharma, R
,
Cardin, J
,
Gaitan, Y
Dev Biol
2013
Participants
Input
Lhx1 [nucleoplasm]
(Mus musculus)
Npnt gene [nucleoplasm]
(Mus musculus)
Output
Lhx1:Npnt gene [nucleoplasm]
(Mus musculus)
Orthologous Events
LHX1 binds the NPNT gene (Homo sapiens)
Authored
May, B (2023-03-12)
Created
May, B (2023-03-13)
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