Reactome | H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane]

H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-MMU-983044-25

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

integral component of lumenal side of endoplasmic reticulum membrane

Synonyms

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor, Q85ZW8

Locations in the PathwayBrowser

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Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Class I MHC mediated antigen processing & presentation (Mus musculus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Mus musculus)
      - Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Budding of COPII coated vesicle (Mus musculus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Mus musculus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Formation of peptide loading complex (PLC) (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Interaction of beta-2-microglobulin (B2M) chain with class I HC (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Loading of antigenic peptides on to class I MHC (Mus musculus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Mus musculus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Transport of MHC heterotrimer to ER exit site (Mus musculus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q85ZW8

Gene Names

H2-M10.4

Reference Genes

BioGPS Gene:224753 H2-M10.4

CTD Gene:224753 H2-M10.4

ENSEMBL:ENSMUSG00000048231

ENSEMBL:ENSMUSG00000048231.15 H2-M10.4

KEGG Gene (Mus musculus):224753 H2-M10.4

Monarch:224753 H2-M10.4

NCBI Gene:224753 H2-M10.4

UCSC:Q85ZW8 H2-M10.4

Reference Transcript

Other Identifiers

10450779

17344743

224753

4363329

4457506

4639517

4758671

5016786

5032891

5075497

5083822

5264095

5296584

5372719

5571767

5603917

A_52_P393567

A_55_P2037009

GO:0000139

GO:0002376

GO:0002476

GO:0005102

GO:0005576

GO:0005615

GO:0005764

GO:0005765

GO:0005768

GO:0005769

GO:0005773

GO:0005783

GO:0005794

GO:0005886

GO:0009897

GO:0009986

GO:0016020

GO:0030881

GO:0031410

GO:0031901

GO:0032398

GO:0033106

GO:0042288

GO:0042605

GO:0042608

GO:0042610

GO:0042612

GO:0042802

GO:0042803

GO:0043226

GO:0046703

GO:0046978

GO:0046979

GO:0051087

GO:0071889

ILMN_2656625

ILMN_2656626

mMC019111

Participates

as a member of

Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)

Other forms of this molecule

H2-M10.4 [phagocytic vesicle membrane]

H2-M10.4 [integral component of lumenal side of endoplasmic reticulum membrane]

H2-M10.4 [secretory granule membrane]

H2-M10.4 [plasma membrane]

H2-M10.4 [azurophil granule membrane]

H2-M10.4 [ER to Golgi transport vesicle membrane]

H2-M10.4 [Golgi membrane]

H2-M10.4 [plasma membrane]

H2-M10.4 [early endosome membrane]

H2-M10.4 [recycling endosome membrane]

H2-M10.4 [phagocytic vesicle membrane]

Inferred From

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

XP_006524186.1, NP_808302.1

Ensembl

ENSMUST00000057502, ENSMUSG00000048231, ENSMUST00000169950, ENSMUSP00000130832, ENSMUSP00000058686

MGI

1276527

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