Reactome | H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane]

H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-MMU-983044-20

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

integral component of lumenal side of endoplasmic reticulum membrane

Synonyms

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor, Q4KN81

Locations in the PathwayBrowser

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Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Class I MHC mediated antigen processing & presentation (Mus musculus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Mus musculus)
      - Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Budding of COPII coated vesicle (Mus musculus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Mus musculus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Formation of peptide loading complex (PLC) (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Interaction of beta-2-microglobulin (B2M) chain with class I HC (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        MHC class I HC:Calnexin/BiP:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC:Calnexin/BiP [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Loading of antigenic peptides on to class I MHC (Mus musculus)
        
        Antigenic peptide:MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        MHC:B2M peptide loading complex [endoplasmic reticulum membrane] (Mus musculus)
        
        MHC HC:B2M:Erp57 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Mus musculus)
        
        COPII vesicle with MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Sar1p:GTP:Sec23p:Sec24p:Ag bound MHC class I [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
      - Transport of MHC heterotrimer to ER exit site (Mus musculus)
        
        Antigen peptide bound class I MHC:BAP31 oligomer [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Peptide bound class I MHC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        monoglucosylated MHC class I HC [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Class I MHC heavy chain (MHC HC) [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)
        
        H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q4KN81

Gene Names

H2-Q2

Reference Genes

BioGPS Gene:15013 H2-Q2

CTD Gene:15013 H2-Q2

ENSEMBL:ENSMUSG00000091705

ENSEMBL:ENSMUSG00000091705.9 H2-Q2

Monarch:15013 H2-Q2

NCBI Gene:15013 H2-Q2

UCSC:Q4KN81 H2-Q2

Reference Transcript

RefSeq:NM_010392.2 H2-Q2

Other Identifiers

10444802

15013

4348560

4449690

4502502

4532243

4615466

4656635

4805845

4856029

5013478

5230093

5290686

5326852

5388959

5587505

97173_f_at

A_51_P219789

GE1418716

GE1536002

GO:0000139

GO:0002376

GO:0002476

GO:0005102

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005769

GO:0005773

GO:0005783

GO:0005794

GO:0005797

GO:0005886

GO:0006955

GO:0007565

GO:0009897

GO:0009986

GO:0016020

GO:0016021

GO:0019882

GO:0022414

GO:0030670

GO:0030881

GO:0031410

GO:0031901

GO:0032398

GO:0032991

GO:0033106

GO:0035264

GO:0042288

GO:0042605

GO:0042608

GO:0042610

GO:0042612

GO:0042802

GO:0042803

GO:0042824

GO:0043226

GO:0046703

GO:0046978

GO:0046979

GO:0051087

GO:0062061

GO:0070971

GO:0071556

GO:0071889

ILMN_2895301

Participates

as a member of

Homologues of HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Mus musculus)

Other forms of this molecule

H2-Q2 [secretory granule membrane]

H2-Q2 [azurophil granule membrane]

H2-Q2 [ER to Golgi transport vesicle membrane]

H2-Q2 [Golgi membrane]

H2-Q2 [phagocytic vesicle membrane]

H2-Q2 [recycling endosome membrane]

H2-Q2 [plasma membrane]

H2-Q2 [early endosome membrane]

H2-Q2 [integral component of lumenal side of endoplasmic reticulum membrane]

Inferred From

HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [integral component of lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_034522.2

Ensembl

ENSMUSG00000091705, ENSMUSP00000078138, ENSMUST00000074806

MGI

95931

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