Reactome | IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

Stable Identifier

R-MMU-9823936

Type

Complex

Species

Mus musculus

Compartment

endosome membrane

Locations in the PathwayBrowser

Expand all

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

IKBKE:IKBKE [cytosol] (Mus musculus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Mus musculus)

Participates

as an input of

IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Mus musculus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Mus musculus)

as an output of

Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Mus musculus)

Inferred From

IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Homo sapiens)

Cite Us!