Foxa2 binds the Gata4 gene

Stable Identifier
R-MMU-9823870
Type
Reaction [binding]
Species
Mus musculus
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Foxa2 binds the Gata4 gene
Foxa2 binds the G4 enhancer in the second intron of the Gata4 gene and directs expression of Gata4 in the primitive gut tube formed by the definitive endoderm (Rojas et al. 2010).
Literature References
PubMed ID Title Journal Year
20692247 Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer

Black, BL, Xu, SM, Martín, F, Schachterle, W, Rojas, A

Dev Biol 2010
Participants
Input
Output
Orthologous Events
SMAD2,3, FOXA2, TBXT, and GATA6 bind the GATA4 gene (Homo sapiens)
Authored
May, B  (2023-01-11)
Reviewed
Tam, PPL  (2023-02-28)
Salehin, N  (2023-02-28)
Created
May, B  (2023-01-11)
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