Pabpn1 binds oligouridylated mRNA

Stable Identifier
R-MMU-9820880
Type
Reaction [binding]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Pabpn1 binds oligouridylated mRNA
Pabpn1 is expressed during zygotic genome activation, binds terminally uridylated maternal mRNAs, and recruits the 3'-5' exoribonuclease Dis3l2 to degrade the mRNA (Zhao et al. 2022).
Literature References
PubMed ID Title Journal Year
34904664 Nuclear poly(A) binding protein 1 (PABPN1) mediates zygotic genome activation-dependent maternal mRNA clearance during mouse early embryonic development

Zhao, LW, Fan, HY, Zhu, YZ, Shen, L, Pi, SB, Wu, YW

Nucleic Acids Res 2022
Participants
Orthologous Events
Authored
Reviewed
Created
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